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Breast Health
Study of Tamoxifen and Raloxifene (STAR)

Baptist Health participated in the National Cancer Institute and National Surgical Adjuvant Breast and Bowel Project (NSABP) sponsored breast cancer prevention trial, STAR. The study compared Raloxifene to Tamoxifen as prevention of breast cancer. The study continues to monitor participants for seven years after they have begun the study medications. Initial results of the STAR study were released in April, 2006 and show that the drug raloxifene works well in reducing breast cancer risk for postmenopausal women.

Tamoxifen is FDA approved for breast cancer prevention for women at high-risk for the disease. Tamoxifen showed a 50% reduction in breast cancer incidence compared to placebo in the first breast cancer prevention trial conducted by the NSABP. Raloxifene is FDA approved for the prevention of osteoporosis. STAR is the study to answer what role Raloxifene has for breast cancer prevention.

Contact Information
Phone Number
(904) 202-7073

If you are a high-risk woman, you may benefit by taking Tamoxifen. Please consult your physician for your breast cancer prevention options. The following are some of the risk factors for breast cancer:

  • Age - the older you are the more at risk you become.
  • Race - Caucasian women have a higher incidence of breast cancer and African-American women have a higher mortality from breast cancer.
  • Menstrual History - if you started your menstrual cycle before age 12.
  • Childbearing History - if you had your first live birth after the age of 30 or never gave birth.
  • Family History - if you have a first-degree relative (mother, sister or daughter) with breast cancer.
  • Breast Biopsy History - benign or malignant, the greater the number, the greater the risk. Fluid removed from a cyst and sent to pathology is considered a biopsy. {Atypical Hyperplasia or Lobular Carcinoma In Situ (LCIS) on a biopsy is a higher-risk diagnosis.}
For more information about this program or other clinical trials, please visit the following sites or call (904) 202-7073:

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